Tìm theo
Hexamethonium
Các tên gọi khác (1) :
  • N,N,N,N',N',N'-hexamethylhexane-1,6-diaminium
Thuốc Gốc
Small Molecule
CAS: 60-26-4
CTHH: C12H30N2
PTK: 202.38
A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C12H30N2
Phân tử khối
202.38
Monoisotopic mass
202.24089897
InChI
InChI=1S/C12H30N2/c1-13(2,3)11-9-7-8-10-12-14(4,5)6/h7-12H2,1-6H3/q+2
InChI Key
InChIKey=VZJFGSRCJCXDSG-UHFFFAOYSA-N
IUPAC Name
trimethyl[6-(trimethylazaniumyl)hexyl]azanium
Traditional IUPAC Name
hexamethonium
SMILES
C[N+](C)(C)CCCCCC[N+](C)(C)C
Độ tan chảy
290-291
Độ hòa tan
2.24e-05 g/l
logP
-6.6
logS
-7.1
Refractivity
88.55 m3·mol-1
Polarizability
27.43 Å3
Polar Surface Area (PSA)
0
Rotatable Bond Count
7
H Bond Acceptor Count
0
H Bond Donor Count
0
Physiological Charge
2
Number of Rings
0
Bioavailability
1
Rule of Five
true
Dữ Kiện Thương Mại
Nhà Sản Xuất
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB08960
Wikipedia
http://en.wikipedia.org/wiki/Hexamethonium
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