Tìm theo
HE3286
Thuốc Gốc
Small Molecule
Cơ Chế Tác Dụng : Potential mechanisms of action for HE3286 include regulation of NF-kB and increasing the production of regulatory T cells (Treg cells). NF-kB is a well-known transcription factor that controls the production of inflammatory cytokines such as TNF-a and interferon-g. Treg cells are referred to in the scientific literature as the peacekeepers of the body. Their role is to keep the immune system from attacking the body itself. Recent studies of Treg cells indicate that they may play a broader role than simply preventing autoimmune conditions. Manipulation of these cells may offer new treatments for conditions ranging from diabetes and organ rejection to cancer and infectious diseases. In type II diabetes, moderate inhibition of NF-kB improves glucose tolerance. [Press Release - Hollis-Eden Pharmaceuticals]
Dược Động Học :
▧ Absorption :
Up to 25% oral bioavailability in mice.
Chỉ Định : For the treatment of rheumatoid arthritis and type 2 diabetes.
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : Triolex
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05212
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