Tìm theo
Guanosine
Thuốc Gốc
Small Molecule
CAS: 118-00-3
CTHH: C10H13N5O5
PTK: 283.2407
Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate). [Wikipedia]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C10H13N5O5
Phân tử khối
283.2407
Monoisotopic mass
283.091668551
InChI
InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9+/m0/s1
InChI Key
InChIKey=NYHBQMYGNKIUIF-BZKDHIKHSA-N
IUPAC Name
2-amino-9-[(2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
Traditional IUPAC Name
guanosine
SMILES
NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO)[C@H](O)[C@H]2O)C(=O)N1
Độ tan chảy
239 dec °C
Độ hòa tan
700 mg/L (at 18 °C)
logP
-1.90
logS
-1.3
pKa (strongest acidic)
10.16
pKa (Strongest Basic)
1.79
PSA
155.22 Å2
Refractivity
64.62 m3·mol-1
Polarizability
25.99 Å3
Rotatable Bond Count
2
H Bond Acceptor Count
8
H Bond Donor Count
5
Physiological Charge
0
Number of Rings
3
Bioavailability
1
Rule of Five
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB02857
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=453549
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46505099
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00387
Wikipedia
http://en.wikipedia.org/wiki/Guanosine
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