Tìm theo
Fleroxacin
Các tên gọi khác (12 ) :
  • Fleroxacin
  • Fleroxacine
  • Fleroxacino
  • Fleroxacinum
  • Fleroxicin
  • FLRX
  • Megalocin
  • Megalocin (TN)
  • Megalone
  • Megalone (TN)
  • Megalosin
  • Quinodis
enzyme inhibitors, nucleic acid synthesis inhibitors, anti infective agents, quinolones
Thuốc Gốc
Small Molecule
CAS: 79660-72-3
ATC: J01MA08
Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Độ tan chảy
270 dec °C
logP
0.24
caco2 Permeability
-4.81
Dược Lực Học : Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
Cơ Chế Tác Dụng : Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. The inhibition of DNA gyrase and DNA topoisomerase 2 leads ultimately to cell death as these enzymes are required for bacterial DNA replication, transcription, repair, strand supercoiling repair, and recombination.
Dược Động Học :
▧ Absorption :
Rapidly and well absorbed from the gastrointestinal tract after oral administration.
Chỉ Định : Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB04576
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C13179
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D01716
PharmGKB
http://www.pharmgkb.org/drug/PA164774762
Wikipedia
http://en.wikipedia.org/wiki/Fleroxacin
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