Tìm theo
Ferric Carboxymaltose
Các tên gọi khác (3) :
  • Iron Carboxymaltose
  • Iron Dextri-Maltose
  • VIT 45
iron preparations
Thuốc Gốc
Small Molecule
CAS: 9007-72-1
Ferric Carboxymaltose is an iron replacement product and chemically, an iron carbohydrate complex. FDA approved on July 25, 2013.
Dược Lực Học : When measured using positron emission tomography (PET), the red cell uptake of 59-Fe and 52-Fe from INJECTAFER ranged from 61% to 99%. In patients with iron deficiency, the red cell uptake ranged from 91% to 99%. In patients with renal anemia, the red cell uptake ranged from 61% to 84%.
Cơ Chế Tác Dụng : Ferric Carboxymaltose is an iron replacement product and chemically, an iron carbohydrate complex. FDA approved on July 25, 2013. Ferric carboxymaltose is a colloidal iron (III) hydroxide in complex with carboxymaltose, a carbohydrate polymer that release iron.
Dược Động Học :
▧ Absorption :
When a single dose of 100 to 1000 mg of iron was given to iron deficient patients, the maximum serum concentration (Cmax) was 37 μg/mL to 333 μg/mL. These levels were obtained 15 minutes to 1.21 hours post dose (Tmax).
▧ Volume of Distribution :
3 L
▧ Route of Elimination :
Renal elimination of iron was negligible.
▧ Half Life :
7 to 12 hours.
Độc Tính : The most common adverse reactions (>2%) are nausea, hypertension, flushing, hypophosphatemia, and dizziness.
Chỉ Định : Ferric carboxymaltose is a iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron or those who have non-dialysis dependent chronic kidney disease.
Liều Lượng & Cách Dùng : Injection - Intravenous - 780 mg
Dữ Kiện Thương Mại
Nhà Sản Xuất
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB08917
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D08920
National Drug Code Directory
http://www.hipaaspace.com/Medical_Billing/Coding/National.Drug.Codes/PDF/0517-0650-01
Drugs.com
http://www.drugs.com/international/ferric-carboxymaltose.html
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