Tìm theo
Fenspiride
Các tên gọi khác (1) :
  • Eurespal
Thuốc tác dụng trên đường hô hấp
Thuốc Gốc
Small Molecule
CAS: 5053-06-5
CTHH: C15H20N2O2
PTK: 260.3315
Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. It is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis), as well as for maintenance treatment of asthma.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C15H20N2O2
Phân tử khối
260.3315
Monoisotopic mass
260.152477894
InChI
InChI=1S/C15H20N2O2/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13/h1-5H,6-12H2,(H,16,18)
InChI Key
InChIKey=FVNFBBAOMBJTST-UHFFFAOYSA-N
IUPAC Name
8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]dec-2-en-2-ol
Traditional IUPAC Name
pneumorel
SMILES
OC1=NCC2(CCN(CCC3=CC=CC=C3)CC2)O1
Độ tan chảy
232-233
Độ hòa tan
4.20e-01 g/l
logP
0.98
logS
-2.8
pKa (strongest acidic)
7.99
pKa (Strongest Basic)
9.37
PSA
45.06 Å2
Refractivity
74.52 m3·mol-1
Polarizability
29.18 Å3
Rotatable Bond Count
3
H Bond Acceptor Count
4
H Bond Donor Count
1
Physiological Charge
2
Number of Rings
3
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB08979
Wikipedia
http://en.wikipedia.org/wiki/Fenspiride
... loading
... loading