Tìm theo
Fendiline
Thuốc Gốc
Small Molecule
CAS: 13042-18-7
CTHH: C23H25N
PTK: 315.4513
Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C23H25N
Phân tử khối
315.4513
Monoisotopic mass
315.198699805
InChI
InChI=1/C23H25N/c1-19(20-11-5-2-6-12-20)24-18-17-23(21-13-7-3-8-14-21)22-15-9-4-10-16-22/h2-16,19,23-24H,17-18H2,1H3
InChI Key
InChIKey=NMKSAYKQLCHXDK-UHFFFAOYNA-N
IUPAC Name
(3,3-diphenylpropyl)(1-phenylethyl)amine
Traditional IUPAC Name
sensit
SMILES
CC(NCCC(C1=CC=CC=C1)C1=CC=CC=C1)C1=CC=CC=C1
Độ tan chảy
200-201
Độ hòa tan
6.22e-05 g/l
logP
5.83
logS
-6.7
pKa (Strongest Basic)
10.07
PSA
12.03 Å2
Refractivity
102.34 m3·mol-1
Polarizability
37.62 Å3
Rotatable Bond Count
7
H Bond Acceptor Count
1
H Bond Donor Count
1
Physiological Charge
1
Number of Rings
3
Bioavailability
1
MDDR-Like Rule
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB08980
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D07185
Wikipedia
http://en.wikipedia.org/wiki/fendiline
... loading
... loading