Tìm theo
Etofibrate
Các tên gọi khác (1) :
  • Etofibrate
Thuốc Gốc
Small Molecule
CAS: 31637-97-5
CTHH: C18H18ClNO5
PTK: 363.792
Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C18H18ClNO5
Phân tử khối
363.792
Monoisotopic mass
363.087350398
InChI
InChI=1S/C18H18ClNO5/c1-18(2,25-15-7-5-14(19)6-8-15)17(22)24-11-10-23-16(21)13-4-3-9-20-12-13/h3-9,12H,10-11H2,1-2H3
InChI Key
InChIKey=XXRVYAFBUDSLJX-UHFFFAOYSA-N
IUPAC Name
2-(pyridine-3-carbonyloxy)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
Traditional IUPAC Name
etofibrate
SMILES
CC(C)(OC1=CC=C(Cl)C=C1)C(=O)OCCOC(=O)C1=CN=CC=C1
Độ tan chảy
214
Độ hòa tan
3.57e-02 g/l
logP
3.63
logS
-4
pKa (Strongest Basic)
3.24
PSA
74.72 Å2
Refractivity
91.34 m3·mol-1
Polarizability
36.88 Å3
Rotatable Bond Count
9
H Bond Acceptor Count
4
H Bond Donor Count
0
Physiological Charge
0
Number of Rings
2
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB08983
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D07187
Wikipedia
http://en.wikipedia.org/wiki/Etofibrate
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