Tìm theo
Etidocaine
Thuốc Gốc
Small Molecule
CAS: 36637-18-0
CTHH: C17H28N2O
PTK: 276.417
Etidocaine, marketed under the trade name Duranest, is a local anesthetic given by injection during surgical procedures and labor and delivery. Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C17H28N2O
Phân tử khối
276.417
Monoisotopic mass
276.220163528
InChI
InChI=1/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20)
InChI Key
InChIKey=VTUSIVBDOCDNHS-UHFFFAOYNA-N
IUPAC Name
N-(2,6-dimethylphenyl)-2-[ethyl(propyl)amino]butanimidic acid
Traditional IUPAC Name
etidocaine product
SMILES
CCCN(CC)C(CC)C(O)=NC1=C(C)C=CC=C1C
Độ tan chảy
203-203.5
Độ hòa tan
4.57e-02 g/l
logP
2.78
logS
-3.8
pKa (strongest acidic)
4.97
pKa (Strongest Basic)
9.4
PSA
35.83 Å2
Refractivity
88.23 m3·mol-1
Polarizability
33.38 Å3
Rotatable Bond Count
7
H Bond Acceptor Count
3
H Bond Donor Count
1
Physiological Charge
1
Number of Rings
1
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty : AstraZeneca
    Sản phẩm biệt dược : Duranest
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB08987
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D04095
Wikipedia
http://en.wikipedia.org/wiki/Etidocaine
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