Tìm theo
Epratuzumab
Các tên gọi khác (2) :
  • anti-CD22 IgG
  • humanised anti-CD22 antibody
Thuốc Gốc
Biotech
CAS: 205923-57-5
Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monotclonal antibody, LL2 (EPB-2). Potential uses may be found in oncology and in treatment of inflammatory autoimmune disorders, such as lupus (SLE).
Cơ Chế Tác Dụng : Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monotclonal antibody, LL2 (EPB-2). Potential uses may be found in oncology and in treatment of inflammatory autoimmune disorders, such as lupus (SLE). Epratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).
Chỉ Định : Investigated for use/treatment in leukemia (lymphoid), lymphoma (non-hodgkin's), and systemic lupus erythematosus.
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : LymphoCide
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB04958
Wikipedia
http://en.wikipedia.org/wiki/Epratuzumab
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