Tìm theo
Enviomycin
Các tên gọi khác (5 ) :
  • Enviomicina
  • Enviomycin
  • Enviomycine
  • Enviomycinum
  • Tuberactinomycin N
Thuốc Gốc
Small Molecule
CAS: 33103-22-9
CTHH: C25H43N13O10
PTK: 685.69
Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C25H43N13O10
Phân tử khối
685.69
Monoisotopic mass
685.325584661
InChI
InChI=1S/C25H43N13O10/c26-3-1-16(41)10(27)5-17(42)33-12-6-31-23(47)18(11-2-4-30-24(28)37-11)38-20(44)13(7-32-25(29)48)34-21(45)14(8-39)36-22(46)15(9-40)35-19(12)43/h7,10-12,14-16,18,39-41H,1-6,8-9,26-27H2,(H,31,47)(H,33,42)(H,34,45)(H,35,43)(H,36,46)(H,38,44)(H3,28,30,37)(H3,29,32,48)/b13-7-/t10-,11-,12+,14+,15+,16-,18+/m1/s1
InChI Key
InChIKey=HPWIIERXAFODPP-GHBBWTPBSA-N
IUPAC Name
(3R,4R)-3,6-diamino-4-hydroxy-N-[(3S,6Z,9S,12S,15S)-2,5,8,11,14-pentahydroxy-6-{[(C-hydroxycarbonimidoyl)amino]methylidene}-9,12-bis(hydroxymethyl)-3-[(4R)-2-imino-1,3-diazinan-4-yl]-1,4,7,10,13-pentaazacyclohexadeca-1,4,7,10,13-pentaen-15-yl]hexanimidic acid
Traditional IUPAC Name
(3R,4R)-3,6-diamino-4-hydroxy-N-[(3S,6Z,9S,12S,15S)-2,5,8,11,14-pentahydroxy-6-[(C-hydroxycarbonimidoylamino)methylidene]-9,12-bis(hydroxymethyl)-3-[(4R)-2-imino-1,3-diazinan-4-yl]-1,4,7,10,13-pentaazacyclohexadeca-1,4,7,10,13-pentaen-15-yl]hexanimidic acid
SMILES
[H]\C(NC(O)=N)=C1\N=C(O)[C@]([H])(CO)N=C(O)[C@]([H])(CO)N=C(O)[C@]([H])(CN=C(O)[C@@]([H])(N=C1O)[C@@]1([H])CCNC(=N)N1)N=C(O)C[C@@]([H])(N)[C@]([H])(O)CCN
Độ hòa tan
1.55e-01 g/l
logP
-9.6
logS
-3.6
pKa (strongest acidic)
2.5
pKa (Strongest Basic)
11.74
PSA
412.29 Å2
Refractivity
186.22 m3·mol-1
Polarizability
65.21 Å3
Rotatable Bond Count
10
H Bond Acceptor Count
23
H Bond Donor Count
17
Physiological Charge
3
Number of Rings
2
Bioavailability
0
Dữ Kiện Thương Mại
Nhà Sản Xuất
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB08993
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D07897
Wikipedia
http://en.wikipedia.org/wiki/Enviomycin
Drugs.com
http://www.drugs.com/international/enviomycin.html
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