Tìm theo
Diminazene
Các tên gọi khác (6 ) :
  • 1,3-TRIS-(4'AMIDINOPHENYL)TRIAZINE
  • 4,4'-(1-Triazene-1,3-diyl)bis-benzenecarboximidamide
  • 4,4'-(Diazoamino)benzamidine
  • Diminazene aceturate
  • Diminazine
  • Diminazine aceturate
trypanocidal agents
Thuốc Gốc
Small Molecule
CAS: 536-71-0
CTHH: C14H15N7
PTK: 281.3158
Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-Triazene-1,3-diyl)bis-benzenecarboximidamide, Diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a solid. This compound belongs to the phenylhydrazines. These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent attached to a phenyl group. Known drug targets of diminazene include HTH-type transcriptional regulator QacR, trypsin-1, amiloride-sensitive amine oxidase [copper-containing], and mitochondrial peroxiredoxin-5.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C14H15N7
Phân tử khối
281.3158
Monoisotopic mass
281.138893515
InChI
InChI=1S/C14H15N7/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18)(H,19,20)
InChI Key
InChIKey=XNYZHCFCZNMTFY-UHFFFAOYSA-N
IUPAC Name
4-[(2E)-3-(4-carbamimidoylphenyl)triaz-2-en-1-yl]benzene-1-carboximidamide
Traditional IUPAC Name
diminazene
SMILES
NC(=N)C1=CC=C(N\N=N\C2=CC=C(C=C2)C(N)=N)C=C1
Độ hòa tan
1.02e-01 g/l
logP
1.76
logS
-3.4
pKa (strongest acidic)
18.96
pKa (Strongest Basic)
12.07
PSA
136.49 Å2
Refractivity
108.73 m3·mol-1
Polarizability
30.17 Å3
Rotatable Bond Count
5
H Bond Acceptor Count
7
H Bond Donor Count
5
Physiological Charge
2
Number of Rings
2
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : Azidin
  • Công ty :
    Sản phẩm biệt dược : Berenil
  • Công ty :
    Sản phẩm biệt dược : Ganasag
  • Công ty :
    Sản phẩm biệt dược : Pirocide
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB03608
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=2354
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46504758
ChemSpider
http://www.chemspider.com/Chemical-Structure.2264.html
BindingDB
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033170
Wikipedia
http://en.wikipedia.org/wiki/Diminazene
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