Tìm theo
Dimethyltryptamine
serotonin receptor agonists
Thuốc Gốc
Small Molecule
CAS: 61-50-7
CTHH: C12H16N2
PTK: 188.2688
An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C12H16N2
Phân tử khối
188.2688
Monoisotopic mass
188.131348522
InChI
InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3
InChI Key
InChIKey=DMULVCHRPCFFGV-UHFFFAOYSA-N
IUPAC Name
[2-(1H-indol-3-yl)ethyl]dimethylamine
Traditional IUPAC Name
dimethyltryptamine
SMILES
CN(C)CCC1=CNC2=CC=CC=C12
Độ tan chảy
46 °C
Độ hòa tan
1.69e+00 g/l
logP
2.3
logS
-2
pKa (strongest acidic)
17.16
pKa (Strongest Basic)
9.55
PSA
19.03 Å2
Refractivity
60.44 m3·mol-1
Polarizability
22.32 Å3
Rotatable Bond Count
3
H Bond Acceptor Count
1
H Bond Donor Count
1
Physiological Charge
1
Number of Rings
2
Bioavailability
1
Rule of Five
true
Ghose Filter
true
pKa
8.68
Cơ Chế Tác Dụng : An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others. [PubChem] DMT acts as a non-selective agonist at most or all of the serotonin receptors.
Chỉ Định : Some people use this compound as a psychedelic inducing agent.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB01488
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=6089
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46507463
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C08302
ChemSpider
http://www.chemspider.com/Chemical-Structure.5864.html
Wikipedia
http://en.wikipedia.org/wiki/Dimethyltryptamine
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