Dược Động Học :
▧ Absorption :
Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.
▧ Protein binding :
Bound to plasma proteins in varying degrees.
▧ Metabolism :
Metabolized, primarily in the liver, and then excreted by the kidneys.