Tìm theo
desmethylprodine
Các tên gọi khác (5 ) :
  • 1-Methyl-4-phenyl-4-piperidinol propionate
  • 1-Methyl-4-phenyl-4-propionoxypiperidine
  • 3-Demethylprodine
  • MPPP
  • PPMP
Thuốc Gốc
Small Molecule
CAS: 13147-09-6
CTHH: C15H21NO2
PTK: 247.3327
Desmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine. It has been listed as a Schedule I controlled drug in the United States, and thus is not used clinically. It is known to be a designer drug, synthesized in 1977, for the purpose of recreational use. Illicit manufacturing has occurred.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C15H21NO2
Phân tử khối
247.3327
Monoisotopic mass
247.157228921
InChI
InChI=1S/C15H21NO2/c1-3-14(17)18-15(9-11-16(2)12-10-15)13-7-5-4-6-8-13/h4-8H,3,9-12H2,1-2H3
InChI Key
InChIKey=BCQMRZRAWHNSBF-UHFFFAOYSA-N
IUPAC Name
1-methyl-4-phenylpiperidin-4-yl propanoate
Traditional IUPAC Name
MPPP
SMILES
CCC(=O)OC1(CCN(C)CC1)C1=CC=CC=C1
Độ hòa tan
1.22e+00 g/l
logP
2.3
logS
-2.3
pKa (Strongest Basic)
8.58
PSA
29.54 Å2
Refractivity
71.99 m3·mol-1
Polarizability
28.04 Å3
Rotatable Bond Count
4
H Bond Acceptor Count
2
H Bond Donor Count
0
Physiological Charge
1
Number of Rings
2
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Độc Tính : A toxic impurity which may be encountered in desmethylprodine synthesis, MPTP, is implicated in the destruction of brain tissue in the substantia nigra, and has lead to permanent Parkinsonian symptoms. [1]
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB01478
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=61583
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46504635
ChemSpider
http://www.chemspider.com/Chemical-Structure.55493.html
Wikipedia
http://en.wikipedia.org/wiki/Desmethylprodine
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