Tìm theo
Deoxythymidine
Các tên gọi khác (4 ) :
  • 2'-Deoxythymidine
  • deoxyribosylthymine
  • Thymidine
  • thymine deoxyriboside
Thuốc Gốc
Small Molecule
CAS: 50-89-5
CTHH: C10H14N2O5
PTK: 242.2286
Deoxythymidine is a pyrimidine deoxynucleoside. Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in S phase.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C10H14N2O5
Phân tử khối
242.2286
Monoisotopic mass
242.090271568
InChI
InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8-/m1/s1
InChI Key
InChIKey=IQFYYKKMVGJFEH-GJMOJQLCSA-N
IUPAC Name
1-[(2R,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
Traditional IUPAC Name
deoxythymidine
SMILES
CC1=CN([C@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O
Độ tan chảy
186.5 °C
Độ hòa tan
6.68e+01 g/l
logP
-0.93
logS
-0.56
pKa (strongest acidic)
9.96
pKa (Strongest Basic)
-3
PSA
99.1 Å2
Refractivity
55.41 m3·mol-1
Polarizability
23 Å3
Rotatable Bond Count
2
H Bond Acceptor Count
5
H Bond Donor Count
3
Physiological Charge
0
Number of Rings
2
Bioavailability
1
Rule of Five
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB04485
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=3000346
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46507598
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00214
BindingDB
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=1
Wikipedia
http://en.wikipedia.org/wiki/Thymidine
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