Tìm theo
D-Tryptophan
Thuốc Gốc
Small Molecule
CAS: 153-94-6
CTHH: C11H11N2O2
PTK: 203.2172
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C11H11N2O2
Phân tử khối
203.2172
Monoisotopic mass
203.082052606
InChI
InChI=1S/C11H11N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9H,5,12H2,(H,14,15)/t9-/m0/s1
InChI Key
InChIKey=UMQXPTSGLUXAQK-VIFPVBQESA-N
IUPAC Name
(2S)-2-amino-3-(indol-3-yl)propanoic acid
Traditional IUPAC Name
D-tryptophan
SMILES
N[C@@H](Cc1cnc2ccccc12)C(O)=O
Độ tan chảy
282-85 dec °C
Độ hòa tan
1.36e+00 g/l
logP
-1.4
logS
-2.2
pKa (strongest acidic)
2.15
pKa (Strongest Basic)
9.32
PSA
76.21 Å2
Refractivity
54.69 m3·mol-1
Polarizability
20.78 Å3
Rotatable Bond Count
3
H Bond Acceptor Count
4
H Bond Donor Count
2
Physiological Charge
0
Number of Rings
2
Bioavailability
1
Rule of Five
true
Tương Tác Thuốc :
  • Zolmitriptan Use of two serotonin modulators, such as zolmitriptan and D-tryptophan, increases the risk of serotonin syndrome. Consider alternate therapy or monitor for serotonin syndrome during concomitant therapy.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB03225
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=6305
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508031
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00525
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