Tìm theo
D-Sorbitol
Thuốc Gốc
Small Molecule
CAS: 50-70-4
CTHH: C6H14O6
PTK: 182.1718
A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. It is also used in many manufacturing processes, as a pharmaceutical aid, and in several research applications. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C6H14O6
Phân tử khối
182.1718
Monoisotopic mass
182.07903818
InChI
InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
InChI Key
InChIKey=FBPFZTCFMRRESA-JGWLITMVSA-N
IUPAC Name
(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol
Traditional IUPAC Name
D-sorbitol
SMILES
OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
Độ tan chảy
111
Độ hòa tan
2.75E+006 mg/L (at 30 °C)
logP
-2.20
logS
1.09
pKa (strongest acidic)
12.59
pKa (Strongest Basic)
-3
PSA
121.38 Å2
Refractivity
38.4 m3·mol-1
Polarizability
17.12 Å3
Rotatable Bond Count
5
H Bond Acceptor Count
6
H Bond Donor Count
6
Physiological Charge
0
Number of Rings
0
Bioavailability
1
pKa
13.6
Dược Động Học :

▧ Route of Elimination :
Sorbitol will either be excreted in the urine by the kidneys, or metabolized to carbon dioxide and dextrose.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB01638
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=5780
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46507030
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00794
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D00096
ChemSpider
http://www.chemspider.com/Chemical-Structure.440.html
National Drug Code Directory
http://www.hipaaspace.com/Medical_Billing/Coding/National.Drug.Codes/PDF/0264-2301-50
PharmGKB
http://www.pharmgkb.org/drug/PA451455
Wikipedia
http://en.wikipedia.org/wiki/Sorbitol
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