Tìm theo
Cyamemazine
Thuốc Gốc
Small Molecule
CAS: 3546-03-0
CTHH: C19H21N3S
PTK: 323.455
Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety. Cyamemazine actually behaves like an atypical antipsychotic, due to its potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C19H21N3S
Phân tử khối
323.455
Monoisotopic mass
323.145618377
InChI
InChI=1/C19H21N3S/c1-14(12-21(2)3)13-22-16-6-4-5-7-18(16)23-19-9-8-15(11-20)10-17(19)22/h4-10,14H,12-13H2,1-3H3
InChI Key
InChIKey=SLFGIOIONGJGRT-UHFFFAOYNA-N
IUPAC Name
10-[3-(dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile
Traditional IUPAC Name
cyamemazine
SMILES
CC(CN(C)C)CN1C2=CC=CC=C2SC2=C1C=C(C=C2)C#N
Độ tan chảy
204-205
Độ hòa tan
2.90e-02 g/l
logP
4.27
logS
-4
pKa (Strongest Basic)
9.42
PSA
30.27 Å2
Refractivity
99.09 m3·mol-1
Polarizability
36.48 Å3
Rotatable Bond Count
4
H Bond Acceptor Count
3
H Bond Donor Count
0
Physiological Charge
1
Number of Rings
3
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Dữ Kiện Thương Mại
Nhà Sản Xuất
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB09000
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D07307
Wikipedia
http://en.wikipedia.org/wiki/Cyamemazine
Drugs.com
http://www.drugs.com/international/cyamemazine.html
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