Cơ Chế Tác Dụng :
Cx501 is used to treat epidermolysis bullosa (EB), a rare genetic condition which can lead to contraction of the joints, fusion of fingers and toes, contraction of the mouth membranes and narrowing of the oesophagus. It is developed by Cellerix and is in phase I of clinical trials.
Cx501 is an artificial skin graft obtained from bringing together keratinocytes from the patient and skin fibroblasts from a healthy donor. Both components are embedded in a plasma matrix which provides the adequate environment for natural healing to occur. These healthy fibroblasts provide the patient with the structural protein that is lacking in the skin of Epidermolysis bullosa (EB)patients.
Chỉ Định :
Investigated for use/treatment in skin infections/disorders.