Dược Lực Học :
CGC-11047 is a polyamine analog with anti-proliferative properties. Polyamines are cell components considered essential for cell proliferation and differentiation. They are believed to work by displacing polyamines from their natural binding sites and preventing cell replication. CGC-11047 has been very well-tolerated in Phase I clinical trials and has demonstrated promising activity in patients with advanced disease.
Cơ Chế Tác Dụng :
CGC-11047 is a polyamine analog designed to halt cell growth and induce apoptosis.
The mechanism of action of CGC-11047 is unknown but it is believed to block the growth of cancer cells by blocking the production of new DNA in the cancer cells.
Chỉ Định :
Investigated for use/treatment in lymphoma (unspecified), macular degeneration, prostate cancer, and solid tumors.