Tìm theo
CCX282
Thuốc Gốc
Small Molecule
CCX282, is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD.
Cơ Chế Tác Dụng : CCX282, is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD. CCX282, a small molecule, orally-available drug, is intended to control the inappropriate immune system response underlying IBD by blocking the activity of the CCR9 chemokine receptor. In adults, CCR9 is a highly specific receptor expressed by T cells that migrate selectively to the digestive tract. The trafficking of T cells to the small and large intestine causes persistent inflammation that may result in Crohn's disease or ulcerative colitis - the two principal forms of IBD.
Chỉ Định : Investigated for use/treatment in crohn's disease, inflammatory bowel disease, and ulcerative colitis.
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : Traficet-EN
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05005
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