Tìm theo
C31G
Thuốc Gốc
Small Molecule
CTHH: C30H64N2O3
PTK: 500.8408
C31G is a potent broad spectrum antimicrobial agent, effective against gram positive and gram negative bacteria, yeast and fungi.C31G, vaginal gel is developed by Biosyn Inc. and has commenced enrollment in a phase III pivotal clinical trial for the reduction of sexual transmission of human immunodeficiency virus (HIV).
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C30H64N2O3
Phân tử khối
500.8408
Monoisotopic mass
500.491693924
InChI
InChI=1S/C16H33NO2.C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-17(2,3)15-16(18)19;1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-15H2,1-3H3;4-14H2,1-3H3
InChI Key
InChIKey=KMCBHFNNVRCAAH-UHFFFAOYSA-N
IUPAC Name
N,N-dimethyldodecanamine oxide 2-(dodecyldimethylazaniumyl)acetate
Traditional IUPAC Name
lauryldimethylamine oxide 2-(dodecyldimethylaminio)acetate
SMILES
CCCCCCCCCCCC[N+](C)(C)[O-].CCCCCCCCCCCC[N+](C)(C)CC([O-])=O
logP
0.39
pKa (strongest acidic)
2.62
PSA
40.13 Å2
Refractivity
103.5 m3·mol-1
Polarizability
34.92 Å3
Rotatable Bond Count
24
H Bond Acceptor Count
2
H Bond Donor Count
0
Physiological Charge
0
Number of Rings
0
Bioavailability
0
Cơ Chế Tác Dụng : C31G is a potent broad spectrum antimicrobial agent, effective against gram positive and gram negative bacteria, yeast and fungi.C31G, vaginal gel is developed by Biosyn Inc. and has commenced enrollment in a phase III pivotal clinical trial for the reduction of sexual transmission of human immunodeficiency virus (HIV). The range of organisms killed by C31G has been extended to include enveloped viruses. Coupled with data indicating a low toxicity for mammalian cells, and a much wider range of anti-microbial activity than Nonoxynol-9, it appears that C31G is an ideal agent for use in decreasing the risk of transmission of organisms associated with STD. C31G is developed as a topical vaginal microbicide with broad-spectrum antibacterial and antiviral properties. C31G which has a high affinity for bacteria, fungi, yeast, and viruses while exhibiting low mammalian cell toxicity.
Chỉ Định : Investigated for use/treatment in contraception, HIV infection, and prevention of stdis.
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : Savvy
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05398
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=456362
ChemSpider
http://www.chemspider.com/Chemical-Structure.401828.html
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