Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
Traditional IUPAC Name
pKa (Strongest Basic)
Dược Lực Học :
Bethanidine is a guanidinium antihypertensive agent that acts by blocking adrenergic transmission. The precise mode of action is not clear. Although bethanidine may produce adverse effects, they are beneficial in severe hypertension and produce fewer side effects than guanethidine.
Cơ Chế Tác Dụng :
A guanidinium antihypertensive agent that acts by blocking adrenergic transmission.
Bethanidine, a guanidine derivative, is a peripherally acting antiadrenergic agent which primarily acts as an alpha2a adrenergic agonist. Bethanidine effectively decreases blood pressure by suppressing renin secretion or interfering with function of the sympathetic nervous system.
Dược Động Học :
▧ Absorption :
Absorbed rapidly in the gastrointestinal tract following oral administration.
▧ Half Life :
9 hours (range 7 to 11 hours)
Chỉ Định :
For the treatment of hypertension.
Liều Lượng & Cách Dùng :
Tablet - Oral