Tìm theo
Betameprodine
Các tên gọi khác (14 ) :
  • 4-piperidinol, 3-ethyl-1-methyl-4-phenyl-, propionate ester
  • (3-ethyl-1-methyl-4-phenyl-piperidin-4-yl) propanoate
  • (3-ethyl-1-methyl-4-phenylpiperidin-4-yl) propanoate
  • 207-407-4
  • 468-50-8
  • AC1L1UK6
  • beta-1-Methyl-3-ethyl-4-phenyl-4-propionoxy-piperidin
  • beta-3-Ethyl-1-methyl-4-phenyl-4-propionoxypiperidine
  • Betameprodina
  • Betameprodinum
  • Meprodine
  • Nu 1732
  • Nu-1932
  • propionic acid (3-ethyl-1-methyl-4-phenyl-4-piperidyl) ester
Thuốc Gốc
Small Molecule
CAS: 468-50-8
CTHH: C17H25NO2
PTK: 275.3859
Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used. Betameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation -- as well as itching, nausea, and respiratory depression.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C17H25NO2
Phân tử khối
275.3859
Monoisotopic mass
275.188529049
InChI
InChI=1S/C17H25NO2/c1-4-14-13-18(3)12-11-17(14,20-16(19)5-2)15-9-7-6-8-10-15/h6-10,14H,4-5,11-13H2,1-3H3
InChI Key
InChIKey=ODEGQXRCQDVXSJ-UHFFFAOYSA-N
IUPAC Name
3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate
Traditional IUPAC Name
3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate
SMILES
CCC1CN(C)CCC1(OC(=O)CC)C1=CC=CC=C1
Độ sôi
354.295 °C at 760 mmHg
Độ hòa tan
1.43 mg/L at 25°C
logP
3.61
logS
-3.1
pKa (Strongest Basic)
9.1
PSA
29.54 Å2
Refractivity
81.01 m3·mol-1
Polarizability
31.8 Å3
Rotatable Bond Count
5
H Bond Acceptor Count
2
H Bond Donor Count
0
Physiological Charge
1
Number of Rings
2
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB01552
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=61118
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46505637
ChemSpider
http://www.chemspider.com/Chemical-Structure.55066.html
Wikipedia
http://en.wikipedia.org/wiki/Betameprodine
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