Tìm theo
Benzyl alcohol
Các tên gọi khác (20 ) :
  • (Hydroxymethyl)benzene
  • Alcoholum benzylicum
  • Alcool benzylique
  • Alcoolbenzylique
  • alpha-Hydroxytoluene
  • alpha-Toluenol
  • Aromatic alcohol
  • Bentalol
  • Benzalalcohol
  • Benzalcohol
  • Benzenecarbinol
  • Benzenemethanol
  • Benzoyl alcohol
  • Benzyl alcohol
  • Benzylalkohol
  • Benzylic alcohol
  • Hydroxymethylbenzene
  • Phenylcarbinol
  • Phenylmethanol
  • Phenylmethyl alcohol
Thuốc gây mê
Thuốc Gốc
Small Molecule
CAS: 100-51-6
CTHH: C7H8O
PTK: 108.1378
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C7H8O
Phân tử khối
108.1378
Monoisotopic mass
108.057514878
InChI
InChI=1S/C7H8O/c8-6-7-4-2-1-3-5-7/h1-5,8H,6H2
InChI Key
InChIKey=WVDDGKGOMKODPV-UHFFFAOYSA-N
IUPAC Name
phenylmethanol
Traditional IUPAC Name
benzyl alcohol
SMILES
OCC1=CC=CC=C1
Độ tan chảy
-15..2 °C, 258 K, 5 °F
Độ sôi
205.3 °C, 478 K, 402 °F
Độ hòa tan
33 mg/mL, clear, colorless
logP
1.1
logS
-0.61
pKa (strongest acidic)
15.02
pKa (Strongest Basic)
-2.8
PSA
20.23 Å2
Refractivity
32.87 m3·mol-1
Polarizability
11.89 Å3
Rotatable Bond Count
1
H Bond Acceptor Count
1
H Bond Donor Count
1
Physiological Charge
0
Number of Rings
1
Bioavailability
1
Rule of Five
true
pKa
15.4
Cơ Chế Tác Dụng : Benzyl alcohol inhibits lice from closing their respiratory spiracles, allowing the vehicle to obstruct the spiracles and causing the lice to asphyxiate.
Độc Tính : 1250 mg/kg (rat, oral) LD50 400 mg/kg IPR-RAT LD50 2000 mg/kg SKN-RBT LD50 53 mg/kg IVN-RAT LD50 2500 mg/kg ORL-GPG LD50
Chỉ Định : Ulesfia (benzyl alcohol) lotion is indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Ulesfia Lotion does not have ovicidal activity.
Liều Lượng & Cách Dùng : Lotion - Topical - 5%
Dữ Kiện Thương Mại
Nhà Sản Xuất
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB06770
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D00077
National Drug Code Directory
http://www.hipaaspace.com/Medical_Billing/Coding/National.Drug.Codes/PDF/59630-780-08
Wikipedia
http://en.wikipedia.org/wiki/Benzyl_alcohol
RxList
http://www.rxlist.com/ulesfia-drug.htm
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