Tìm theo
Bentoquatam
skin and mucous membrane agents
Thuốc Gốc
Small Molecule
CAS: 1340-69-8
CTHH: Al2H2O6Si
PTK: 180.0609
Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak. Bentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
Al2H2O6Si
Phân tử khối
180.0609
Monoisotopic mass
179.925141211
InChI
InChI=1S/2Al.O2Si.H2O.3O/c;;1-3-2;;;;/h;;;1H2;;;
InChI Key
InChIKey=SVPXDRXYRYOSEX-UHFFFAOYSA-N
IUPAC Name
oxo[(oxoalumanyl)oxy]alumane silanedione hydrate
Traditional IUPAC Name
oxo[(oxoalumanyl)oxy]alumane silica hydrate
SMILES
O.O=[Si]=O.O=[Al]O[Al]=O
Độ hòa tan
Soluble
logP
2.47
pKa (Strongest Basic)
-3
PSA
43.37 Å2
Refractivity
4.24 m3·mol-1
Polarizability
6.44 Å3
Rotatable Bond Count
2
H Bond Acceptor Count
2
H Bond Donor Count
0
Physiological Charge
0
Number of Rings
0
Bioavailability
1
Rule of Five
true
Dược Lực Học : Bentoquatam protects the skin like a shield against poison ivy, poison oak, and poison sumac by physically blocking skin contact with their resin. The best protection against getting these conditions is to avoid contact with these plants. This medicine does not dry oozing and weeping caused by the rash of poison ivy, poison oak, or poison sumac.
Cơ Chế Tác Dụng : Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak. Bentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin. The mechanism of action is unknown. It is thought topically applied bentoquatam acts as a physical barrier that interferes with the adsorption of antigens onto the skin and reduces absorption of antigens into the skin. It probably does not work by modifying the systemic allergic response.
Độc Tính : Rare side effects include mild erythema (mild redness of skin).
Chỉ Định : Used to prevent or reduce the severity of allergic contact dermatitis due to urushiol, the allergenic resin of poison ivy, poison oak, and poison sumac.
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty : Hyland's
    Sản phẩm biệt dược : IvyBlock
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB00516
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=517273
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508055
ChemSpider
http://www.chemspider.com/Chemical-Structure.451302.html
PharmGKB
http://www.pharmgkb.org/drug/PA164748098
Wikipedia
http://en.wikipedia.org/wiki/Bentoquatam
Drugs.com
http://www.drugs.com/mtm/bentoquatam-topical.html
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