Cơ Chế Tác Dụng :
Autologous activated macrophage therapy is used to treat patients with acute complete spinal cord injury.
Autologous activated macrophage therapy consists of macrophages isolated from the patient's own blood, co-incubated with the patient's skin in a proprietary process and then injected directly into the patient's injured spinal cord.
Macrophages are white blood cells that play a beneficial role in wound healing and tissue regeneration throughout the body. However, within the brain and spinal cord, resident macrophage activity appears to be inhibited, severely restricting the capacity for spontaneous regeneration. The strategy employed by Proneuron is to overcome the restriction on nerve regeneration by collecting autologous (taken from the patient himself) macrophages directly from the blood, activating them in the laboratory and then implanting them in the site of the injury.
Chỉ Định :
Investigated for use/treatment in spinal cord injuries.