Dược Động Học :
▧ Absorption :
T-cell depletion usually observed within 1 day after initiating therapy.
Average 21.5 and 87 mcg/mL 4–8 hours post-infusion after first and last IV doses, respectively, when given for 7–11 days.
▧ Metabolism :
Most likely removed by opsonization via the reticuloendothelial system when bound to T lymphocytes, or by human antimurine antibody production.
▧ Half Life :
2-3 days, may increase after multiple doses administration