Tìm theo
Afelimomab
Các tên gọi khác (2) :
  • Fab 2
  • MAK 195F
Thuốc Gốc
Biotech
CAS: 156227-98-4
ATC: L04AB03
Afelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.
Dược Lực Học : Afelimomab is the F(ab')2 fragment of a murine anti-TNF-alpha antibody, and has been evaluated in clinical trials in septic patients. The results suggest that the drug is well tolerated, and may be of benefit in certain groups of patients with sepsis. Afelimomab is safe, biologically active, and well tolerated in patients with severe sepsis, reduces 28-day all-cause mortality, and attenuates the severity of organ dysfunction in patients with elevated interleukin-6 levels.
Dược Động Học :

▧ Half Life :
44.7 hours
Chỉ Định : Investigated for use/treatment in sepsis and septicemia.
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : Segard
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB04956
Wikipedia
http://en.wikipedia.org/wiki/Afelimomab
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