Tìm theo
Adenosine triphosphate
Các tên gọi khác (3) :
  • Adenosine 5'-triphosphate
  • Adenosine-5'-triphosphate
  • ATP
dietary supplements, micronutrients, supplements
Thuốc Gốc
Small Molecule
CAS: 56-65-5
CTHH: C10H16N5O13P3
PTK: 507.181
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C10H16N5O13P3
Phân tử khối
507.181
Monoisotopic mass
506.995745159
InChI
InChI=1/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/s2
InChI Key
InChIKey=ZKHQWZAMYRWXGA-YPLCUDRINA-N
IUPAC Name
({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
Traditional IUPAC Name
adenosine triphosphate
SMILES
NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
Độ tan chảy
176 °C
Độ hòa tan
1E+006 mg/L
logP
-5.5
logS
-2
pKa (strongest acidic)
0.9
pKa (Strongest Basic)
5
PSA
279.13 Å2
Refractivity
95.81 m3·mol-1
Polarizability
38.92 Å3
Rotatable Bond Count
8
H Bond Acceptor Count
14
H Bond Donor Count
7
Physiological Charge
-3
Number of Rings
3
Bioavailability
0
MDDR-Like Rule
true
Dược Lực Học : Adenosine triphosphate (ATP) is the nucleotide known in biochemistry as the "molecular currency" of intracellular energy transfer; that is, ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. The total quantity of ATP in the human body is about 0.1 mole. The energy used by human cells requires the hydrolysis of 200 to 300 moles of ATP daily. This means that each ATP molecule is recycled 2000 to 3000 times during a single day. ATP cannot be stored, hence its consumption must closely follow its synthesis.
Cơ Chế Tác Dụng : An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. [PubChem] ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. ATP can be produced by various cellular processes, most typically in mitochondria by oxidative phosphorylation under the catalytic influence of ATP synthase. The total quantity of ATP in the human body is about 0.1 mole. The energy used by human cells requires the hydrolysis of 200 to 300 moles of ATP daily. This means that each ATP molecule is recycled 2000 to 3000 times during a single day. ATP cannot be stored, hence its consumption must closely follow its synthesis.
Độc Tính : Oral LD50 in rats is > 2 g/kg.
Chỉ Định : For nutritional supplementation, also for treating dietary shortage or imbalance
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty : Biochimica
    Sản phẩm biệt dược : Atriphos
  • Công ty : Auclair
    Sản phẩm biệt dược : Striadyne
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB00171
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00002
BindingDB
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2
PharmGKB
http://www.pharmgkb.org/drug/PA164743471
Wikipedia
http://en.wikipedia.org/wiki/Adenosine_triphosphate
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