Acylated Ceftazidime
Thuốc Gốc
Small Molecule
CTHH: C17H19N5O7S2
PTK: 469.492
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
Phân tử khối
469.492
Monoisotopic mass
469.072589367
InChI
InChI=1S/C17H19N5O7S2/c1-7-5-30-13(21-10(7)14(25)26)8(4-23)19-12(24)11(9-6-31-16(18)20-9)22-29-17(2,3)15(27)28/h4,6,8,13H,1,5H2,2-3H3,(H2,18,20)(H,19,24)(H,25,26)(H,27,28)/b22-11+/t8-,13+/m1/s1
InChI Key
InChIKey=VEHPZKIFULQYFS-BQFDAFGASA-N
IUPAC Name
(2S)-2-[(1R)-1-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
Traditional IUPAC Name
acylated ceftazidime
SMILES
O=C[C@@H](NC(=O)C(=N\OC(C)(C)C(O)=O)\C1=CSC(N)=N1)[C@@H]1SCC(=C)C(=N1)C(O)=O
Độ hòa tan
3.79e-02 g/l
logP
0.63
logS
-4.1
pKa (strongest acidic)
2.84
pKa (Strongest Basic)
4.3
PSA
193.63 Å2
Refractivity
109.93 m3·mol-1
Polarizability
44.28 Å3
Rotatable Bond Count
9
H Bond Acceptor Count
11
H Bond Donor Count
4
Physiological Charge
-2
Number of Rings
2
Bioavailability
1
Ghose Filter
true
Tài Liệu Tham Khảo Thêm
drugbank
PubChem Compound
PubChem Substance
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