Tìm theo
Acetylcholine
Các tên gọi khác (1) :
  • Acetylcholine Chloride
Thuốc tim mạch
Thuốc Gốc
Small Molecule
CAS: 51-84-3
ĐG : Novartis AG , http://www.novartis.com
CTHH: C7H16NO2
PTK: 146.2074
A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, but it is useful in some ophthalmological applications. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C7H16NO2
Phân tử khối
146.2074
Monoisotopic mass
146.118103761
InChI
InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1
InChI Key
InChIKey=OIPILFWXSMYKGL-UHFFFAOYSA-N
IUPAC Name
[2-(acetyloxy)ethyl]trimethylazanium
Traditional IUPAC Name
acetylcholine
SMILES
CC(=O)OCC[N+](C)(C)C
Độ hòa tan
1.36e-01 g/l
logP
-4.2
logS
-3.1
pKa (Strongest Basic)
-7
PSA
26.3 Å2
Refractivity
51.35 m3·mol-1
Polarizability
16.69 Å3
Rotatable Bond Count
4
H Bond Acceptor Count
1
H Bond Donor Count
0
Physiological Charge
1
Number of Rings
0
Bioavailability
1
Rule of Five
true
Tương Tác Thuốc :
  • Tacrine The acetylcholinesterase inhibitor, Tacrine, may increase the adverse/toxic effects of Acetylcholine, a cholinergic agonist. Monitor for increased cholinergic effects and toxicity.
Dữ Kiện Thương Mại
Đóng gói
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB03128
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=187
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46504484
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C01996
PharmGKB
http://www.pharmgkb.org/drug/PA448031
... loading
... loading