5R-(3,4-DICHLOROPHENYLMETHYL)-3-(2-THIOPHENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE
Thuốc Gốc
Small Molecule
CTHH: C14H10Cl2N2O3S4
PTK: 453.407
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C14H10Cl2N2O3S4
Phân tử khối
453.407
Monoisotopic mass
451.89513037
InChI
InChI=1S/C14H10Cl2N2O3S4/c15-9-4-3-8(6-10(9)16)7-11-13(19)18(14(22)24-11)17-25(20,21)12-2-1-5-23-12/h1-6,11,17H,7H2/t11-/m1/s1
InChI Key
InChIKey=GAOOBYJHWAKZKU-LLVKDONJSA-N
IUPAC Name
N-[(5R)-5-[(3,4-dichlorophenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]thiophene-2-sulfonamide
Traditional IUPAC Name
N-[(5R)-5-[(3,4-dichlorophenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]thiophene-2-sulfonamide
SMILES
[H][C@]1(CC2=CC=C(Cl)C(Cl)=C2)SC(=S)N(NS(=O)(=O)C2=CC=CS2)C1=O
Độ hòa tan
1.18e-03 g/l
logP
5.01
logS
-5.6
pKa (strongest acidic)
3.87
PSA
66.48 Å2
Refractivity
105.13 m3·mol-1
Polarizability
41.5 Å3
Rotatable Bond Count
4
H Bond Acceptor Count
3
H Bond Donor Count
1
Physiological Charge
-1
Number of Rings
3
Bioavailability
1
Ghose Filter
true
Tài Liệu Tham Khảo Thêm
drugbank
PubChem Compound
PubChem Substance
Bạn thấy hài lòng ?
Bạn chưa hài lòng ?
... loading
... loading