Tìm theo
4-Androstenedione
Các tên gọi khác (1) :
  • 4-Androstene-3,17-dione
Thuốc Gốc
Small Molecule
CAS: 63-05-8
CTHH: C19H26O2
PTK: 286.4085
A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C19H26O2
Phân tử khối
286.4085
Monoisotopic mass
286.193280076
InChI
InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
InChI Key
InChIKey=AEMFNILZOJDQLW-QAGGRKNESA-N
IUPAC Name
(1S,2R,10R,11S,15S)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,14-dione
Traditional IUPAC Name
4-androstenedione
SMILES
[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
Độ tan chảy
158 °C
Độ hòa tan
57.8 mg/L (at 25 °C)
logP
2.75
logS
-3.69
pKa (strongest acidic)
19.03
pKa (Strongest Basic)
-4.8
PSA
34.14 Å2
Refractivity
83.61 m3·mol-1
Polarizability
33.2 Å3
Rotatable Bond Count
0
H Bond Acceptor Count
2
H Bond Donor Count
0
Physiological Charge
0
Number of Rings
4
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Cơ Chế Tác Dụng : A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol. [PubChem] 4-androstenedione is a 19-carbon steroid hormone produced in the adrenal glands and the gonads as an intermediate step in the biochemical pathway that produces the androgen testosterone and the estrogens estrone and estradiol.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB01536
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=6128
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508011
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00280
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D00051
ChemSpider
http://www.chemspider.com/Chemical-Structure.5898.html
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