Tìm theo
3-Deoxyguanosine
Thuốc Gốc
Small Molecule
CTHH: C10H13N5O4
PTK: 267.2413
3-deoxyguanosine is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. This medication targets the protein purine nucleoside phosphorylase.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C10H13N5O4
Phân tử khối
267.2413
Monoisotopic mass
267.096753929
InChI
InChI=1S/C10H13N5O4/c11-10-13-7-6(8(18)14-10)12-3-15(7)9-5(17)1-4(2-16)19-9/h3-5,9,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5-,9-/m0/s1
InChI Key
InChIKey=OROIAVZITJBGSM-PJPYAQQDSA-N
IUPAC Name
2-amino-9-[(2S,3S,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
Traditional IUPAC Name
3-deoxyguanosine
SMILES
NC1=NC2=C(N=CN2[C@H]2O[C@H](CO)C[C@@H]2O)C(=O)N1
Độ hòa tan
1.19e+01 g/l
logP
-2
logS
-1.4
pKa (strongest acidic)
10.16
pKa (Strongest Basic)
1.83
PSA
134.99 Å2
Refractivity
63.52 m3·mol-1
Polarizability
25.37 Å3
Rotatable Bond Count
2
H Bond Acceptor Count
7
H Bond Donor Count
4
Physiological Charge
0
Number of Rings
3
Bioavailability
1
Rule of Five
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB03609
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=6541399
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508922
BindingDB
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50144937
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